2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Steroid Sulfatase

Steroid Sulfatase

 

Steroid Sulfatase Related Products (18):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-14586
    Irosustat
    		Inhibitor 99.72%
    Irosustat is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity.
    Irosustat
  • HY-U00112
    Estradiol 3-sulfamate
    		Inhibitor 99.87%
    Estradiol 3-sulfamate (BLE 00084; E2MATE; ES-J 995) is a potent, long-acting, and orally active steroid sulfatase inhibitor; inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM.
    Estradiol 3-sulfamate
  • HY-14585
    Estrone O-sulfamate
    		Inhibitor 99.99%
    Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer.
    Estrone O-sulfamate
  • HY-155234
    Steroid sulfatase-IN-6
    		Inhibitor
    Steroid sulfatase-IN-6 (Compound 10c) is an irreversible inhibitor of steroid sulfatase (STS). Steroid sulfatase-IN-6 has an Ki value of 0.4 nM for human placenta STS. Steroid sulfatase-IN-6 can be used for tumor diseases research.
    Steroid sulfatase-IN-6
  • HY-151201
    Steroid sulfatase/17β-HSD1-IN-3
    		Inhibitor
    Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 irreversibly inhibits hSTS activity with anIC50 value of 27 nM. Steroid sulfatase/17β-HSD1-IN-3 can be used in the study of endometriosis and other estrogen-dependent diseases.
    Steroid sulfatase/17β-HSD1-IN-3
  • HY-P990724
    Tividenofusp alfa
    Tividenofusp alfa is an anti-iduronate 2-sulfatase (ID2S) monoclonal antibody.
    Tividenofusp alfa
  • HY-123420
    Dinordrin
    Dinordrin (Dinordrin I) is a steroid with a luteolytic effect. Dinordrin can cause depression of both plasma estrogen and progesterone levels.
    Dinordrin
  • HY-150542
    Steroid sulfatase-IN-2
    		Inhibitor
    Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer.
    Steroid sulfatase-IN-2
  • HY-156902
    Steroid sulfatase-IN-8
    		Inhibitor
    Steroid sulfatase-IN-8 (7) is a STS inhibitor with PM IC50 value of 1 nM, JEG-3 IC50 of 0.025 nM, respecively.
    Steroid sulfatase-IN-8
  • HY-116377
    DU-14
    		Inhibitor 99.18%
    DU-14 is a potent steroid sulfatase inhibitor with an IC50 of 55.8 nM. DU-14 inhibits the MCF-7 cell proliferation (IC50 = 38.7 nM). DU-14 has neuroprotective effects against neurotoxic Aβ, suggesting that up-regulation of endogenous DHEAS by DU-14 could be beneficial to the alleviation of Aβ-induced impairments in spatial memory and synaptic plasticity.
    DU-14
  • HY-151200
    Steroid sulfatase-IN-4
    		Inhibitor
    Steroid sulfatase-IN-4 (Compound 16) is an irreversible steroid sulfatase (STS) inhibitor with an IC50 of 25 nM against human STS. Steroid sulfatase-IN-4 can be used for the research of endometriosis.
    Steroid sulfatase-IN-4
  • HY-150543
    Steroid sulfatase-IN-3
    		Inhibitor
    Steroid sulfatase-IN-3 (compound 1q) is a potent STS (Steroid sulfatase) inhibitor, with an IC50 of 25.8 nM. Steroid sulfatase-IN-3 shows antiproliferative activity against T-47D estrogen-dependent breast cancer cells, with an IC50 of 1.04 µM.
    Steroid sulfatase-IN-3
  • HY-155235
    Steroid sulfatase-IN-7
    		Inhibitor
    Steroid sulfatase-IN-7 is an irreversible steroid sulfatase (STS) inhibitor with an IC50 value of 0.05 nM against human placental STS and can be used in cancer research.
    Steroid sulfatase-IN-7
  • HY-144656
    Steroid sulfatase-IN-1
    		Inhibitor
    Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 nM. Steroid sulfatase-IN-1 shows antitumor activity in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer.
    Steroid sulfatase-IN-1
  • HY-155010
    Steroid sulfatase/17β-HSD1-IN-5
    		Inhibitor
    Steroid sulfatase/17β-HSD1-IN-5 is a irreversible inhibitor of steroid sulfatase (STS) .Steroid sulfatase/17β-HSD1-IN-5 is a reversible and selective inhibitor of 7β-hydroxysteroid dehydrogenase type1 (17β-HSD1), with IC50s of 43 nM and 6.2μM for 17β-HSD1 and 17β-HSD2, respectively. Steroid sulfatase/17β-HSD1-IN-5 can be used for metabolic disease (especially for endometriosis) research.
    Steroid sulfatase/17β-HSD1-IN-5
  • HY-155233
    Steroid sulfatase-IN-5
    		Inhibitor
    Steroid sulfatase-IN-5 (compound 10b) is a steroid sulfatase (STS) inhibitor (IC50: 0.32 nM). Steroid sulfatase-IN-5 inhibits T-47D cell proliferation with an IC50 of 35.7 μM. Steroid sulfatase-IN-5 can be used for research of breast cancer.
    Steroid sulfatase-IN-5
  • HY-151199
    Steroid sulfatase/17β-HSD1-IN-1
    		Inhibitor
    Steroid sulfatase/17β-HSD1-IN-1 is a potent steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor with an IC50 value of 28 nM for cellular human steroid sulfatase. Steroid sulfatase/17β-HSD1-IN-1 can be used to research estrogen-dependent diseases.
    Steroid sulfatase/17β-HSD1-IN-1
  • HY-151202
    Steroid sulfatase/17β-HSD1-IN-4
    		Inhibitor
    Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS activity with anIC50 value of 63 nM. Steroid sulfatase/17β-HSD1-IN-4 can be used in the study of endometriosis and other estrogen-dependent diseases.
    Steroid sulfatase/17β-HSD1-IN-4